Product & ReviewsAntibodies

anti-CD46 mouse monoclonal, 197-2B1, purified

Product Details

Cat. No.
691589
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
PROGEN

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Description

197-2B1 reacts with human CD46, a 52-58 kDa single chain type 1 transmembrane molecule. CD46 is a cofactor for the factor I regulation of complement components C3b and C4b and contains four N-terminal short consensus repeat (SCR) modules. It is strongly expressed on salivary gland ducts and kidney ducts and often increased on tumor cells. It is also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: stimulated human leucocytes
  • Clone: 197-2B1
  • Conjugate: unconjugated
  • Isotype: IgG2a kappa

Handling

  • Quantity: 1 mL (100 µg/ml)
  • Storage: store at 2-8°C

Applications

  • Flow Cytometry (FC)
  • Immunocytochemistry (ICC)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
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