Anti-CD52 monoclonal antibody, clone YTH34.5 [FITC]
Product Details
- Cat. No.
- CABT-46437RH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
Rat Anti-Human CD52 monoclonal antibody for FC. Rat anti Human CD52 antibody, clone YTH34.5 reacts with the human CD52 antigen, also known as CAMPATH-1. The CD52 antigen is a remarkably small but heavily glycosylated peptide attached to the cell surface membrane via a GPI link. The apparent molecular mass of the native antigen on SDS-PAGE is 25-29kDa, considerably reduced following N-glycanase treatment. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable. Humanised versions of CAMPATH-1 specific antibodies are currently in clinical trials for the treatment of a range of lymphoid malignancies. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Human, Rhesus Monkey
- Conjugate: FITC
- Isotype: IgG2b
- Gene: 1043
Handling
- Quantity: 100 μg
- Storage: in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)