Product & ReviewsAntibodies

Anti-CD8A monoclonal antibody, clone KT15 [Biotin]

Product Details

Cat. No.
CABT-45318RM
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
Creative Diagnostics

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Description

Rat Anti-Mouse CD8A monoclonal antibody for FC. Rat anti mouse CD8α, clone KT15, recognises the alpha chain of mouse CD8. CD8 is a heterodimeric protein composed of disulphide-linked CD8α and CD8β chains that is expressed primarily on cytotoxic T-cells. CD8 functions in the interaction with MHC Class I-bearing targets and plays a role in T-cell-mediated killing. Clone KT15 is reported to block T-cell-mediated cytotoxicity in in vitro assays. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Conjugate: Biotin
  • Isotype: IgG2a
  • Gene: 12525

Handling

  • Quantity: 100 Tests
  • Storage: in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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