Product & ReviewsAntibodies
anti-CD8a mouse monoclonal,143-44, purified
Product Details
- Cat. No.
- 691556
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
143-44 recognizes a protein of 32 kDa, identified as CD8a. The CD8 molecule consists of a and ß-chains, which are disulphide-linked into heterodimers or homodimers. CD8 is expressed on a T-cell subset (cytotoxic/suppressor T-cells), thymocytes and NK-cells. The majority of CD8+ T-cells express CD8 as heterodimer. Some subpopulation of CD8+ T-cells as well as NK-cells may express homodimer. CD8 functions as a co-receptor in concert with TCR for binding the MHC class I/peptide complex
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: human PBL
- Clone: 143-44
- Conjugate: unconjugated
- Isotype: IgG1 kappa
Handling
- Quantity: 1 mL (100 µg/ml)
- Storage: store at 2-8°C
Applications
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)