Anti-Ceruloplasmin polyclonal antibody
Product Details
- Cat. No.
- CPBT-65875SH
- Type
- Primary Antibody
- Clonality
- Polyclonal
- Host
- Sheep
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Description
Sheep Anti-Human Ceruloplasmin polyclonal antibody for IHC-Fr; ELISA. Sheep anti Human ceruloplasmin antibody detects ceruloplasmin, a ~132kDa metalloprotein that is secreted into the plasma by liver hepatocytes and activated monocytes/macrophages. Ceruloplasmin functions in copper transport, iron homeostasis, antioxidant defence, angiogenesis and coagulation. Deficiency in ceruloplasmin is termed aceruloplasminemia, an autosomal recessive disorder which leads to iron accumulation and tissue damage, in particular in the brain and visceral organs. Clinical features include retinal degeneration, diabetes mellitus and neurological disturbances. Elevated plasma ceruloplasmin has been shown to pose an increased risk in atherosclerosis and myocardial infarction. ELISA This antibody has been used at dilutions as high as 1/400K in a simple ELISA with 0.1 μg of antigen coated per well. Applications:IHC-Fr; ELISA
Biological Information
- Clonality: Polyclonal
- Host: Sheep
- Reactivity: Human
- Conjugate: Unconjugated
- Isotype: Polyclonal IgG
- Gene: 1356
Handling
- Quantity: 1 ml
- Storage: in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)