Product & ReviewsAntibodies

Anti-CLEC4N monoclonal antibody, clone D2.11E4 [Biotin]

Product Details

Cat. No.
CABT-47594RM
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
Creative Diagnostics

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Description

Rat anti-Mouse CLEC4N monoclonal antibody for FC. Rat anti Mouse Dectin-2 antibody, clone D2.11E4 recognizes mouse DC-associated C-type lectin-2 (Dectin-2), a type II transmembrane protein that is a member of the C-type lectin superfamily. In mouse, dectin-2 is predominantly expressed on tissue macrophages and some dendritic cells. Clone D2.11E4 does not stain brain microglia or meningeal macrophages. Significant expression of Dectin-2 has been reported on macrophages in the red pulp and marginal zones of the spleen, kupffer cells in the liver and alveolar macrophages in the lung. Peripheral blood monocytes express low levels of dectin-2 but transient up-regulation of expression has been demonstrated on monocytes at sites of inflammation. The function of dectin-2 has not been fully determined but studies suggest a possible role in immune-surveillance. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Conjugate: Biotin
  • Isotype: IgG2a
  • Gene: 56620

Handling

  • Quantity: 100 μg
  • Storage: in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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