Anti-CLEC7A monoclonal antibody, clone 2A11 [Biotin]
Product Details
- Cat. No.
- CABT-47578RM
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
Rat Anti-Mouse CLEC7A monoclonal antibody for FC. Rat anti Mouse Dectin-1 antibody, clone 2A11 recognizes murine beta-glucan receptor, also known as Dectin-1.Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens. Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk. Rat anti Mouse Dectin-1 antibody, clone 2A11 inhibits the binding of zymosan to macrophages via the beta-glucan receptor. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Conjugate: Biotin
- Isotype: IgG2b
- Gene: 56644
Handling
- Quantity: 100 μg
- Storage: in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)