Product & ReviewsAntibodies

Anti-CLEC7A monoclonal antibody, clone 2A11 [R-PE]

Product Details

Cat. No.
CABT-47588RM
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
Creative Diagnostics

The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our  Antibody Directory.

Description

Rat Anti-Mouse CLEC7A monoclonal antibody for FC. Rat anti Mouse Dectin-1 antibody, clone 2A11 recognizes murine beta-glucan receptor, also known as Dectin-1.Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens. Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk. Rat anti Mouse Dectin-1 antibody, clone 2A11 inhibits the binding of zymosan to macrophages via the beta-glucan receptor. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Conjugate: R-PE
  • Isotype: IgG2b
  • Gene: 56644

Handling

  • Quantity: 100 Tests
  • Storage: Store at +4°C. DO NOT FREEZE This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
Specificity rating
Sensitivity rating
Quality rating
Write your own review

Product Overview

Links