Product & ReviewsAntibodies
anti-Desmocollin 1 mouse monoclonal, Dsc1-U100, lyophilized, purified
Product Details
- Cat. No.
- 61092
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mab localizes Dsc1 present insuprabasal layers of interfollicular epidermisspecific cell layers (e.g. in hair follicle root sheath)Hassall bodies (spheroidal formations of densely packed reticulum-derived cells in the thymus).Reacts with 111 kD (form "a") and 103 kD (form "b") polypeptides (desmo-collin 1 splice forms, both at pI 5.2) from human epidermal desmosomes.Reactivity on cultured cell lines: Positive on primary keratinocytes, however, restricted to local piles of differentiated cells
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Mouse, Rat
- Antigen: synthetic peptide corresponding to sequence present within the intracellular part of human desmocollin 1 (HQTLESVKGVGQGDTGRYATDWQC)
- Clone: Dsc1-U100
- Conjugate: unconjugated
- Isotype: IgG1
Handling
- Quantity: 50 µg
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Applications
- Immunohistochemistry (IHC)
- Western Blotting (WB)