Product & ReviewsAntibodies

anti-Desmocollin 3 mouse monoclonal, Dsc3-U114, purified, sample (ready-to-use)

Product Details

Cat. No.
61093S
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
PROGEN

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Description

Mab localizes Dsc3 present inall living epidermal layersin glandular duct cellsin basal matrix cells and outer root sheath of hair folliclesbasal and suprabasal cell layers of stratified epithelia (e.g. vagina, tongue, esophagus), basal layer of bladder urothelium and complex epithelium of tracheathymic reticulum cellsAll simple epithelia are negative. Intercalated disks of myocardium are negative. Polypeptide reacting: 109 kD and 100 kD polypeptides (desmocollin 3 splice isoforms at pI 5.2) from human epidermal desmosomes.Reactivity on cultured cell lines: Most cultured cell lines derived from stratified squamous epithelia or squamous cell carcinomas are positive (e.g. A-431, HaCaT).

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human, Mouse, Rat
  • Antigen: Synthetic peptide corresponding to a sequence present on the extracellular anchor domain of human desmocollin 3 (VHGAPFYFSLPNTSPEISRLWSLTKVC)
  • Clone: Dsc3-U114
  • Conjugate: unconjugated
  • Isotype: IgG1

Handling

  • Quantity: 600 µL (ready-to-use)
  • Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles

Applications

  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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