Product & ReviewsAntibodies

anti-Desmoglein 1/2 mouse monoclonal, DG 3.10, liquid, purified

Product Details

Cat. No.
690002
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
PROGEN

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Description

<p>DG 3.10 recognizes desmoglein 1 + 2 (desmosome-specific cadherins) in desmosome-bearing cells; does not react with cells containing plaque-bearing junctions of non-desmosomal type. Tumors specifically detected: all epithelium-derived tumors, notably carcinomas, and meningiomas. Polypeptide reacting: Mr 165 000 Desmoglein, "band 3" polypeptide of the desmosomal complex. Epitope recognized has been localized at the repeating unit domain ("RUD") of the cytoplasmic C-terminal part of the polypeptide.</p> <p>Reactivity on cultured cell lines: A-431, MDBK.</p>

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse

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