Product & ReviewsAntibodies
anti-Desmoglein 1/2 mouse monoclonal, DG 3.10, liquid, purified, sample
Product Details
- Cat. No.
- 690002S
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
<p>DG 3.10 recognizes desmoglein 1 + 2 (desmosome-specific cadherins) in desmosome-bearing cells; does not react with cells containing plaque-bearing junctions of non-desmosomal type. Tumors specifically detected: all epithelium-derived tumors, notably carcinomas, and meningiomas. Polypeptide reacting: Mr 165 000 Desmoglein, "band 3" polypeptide of the desmosomal complex. Epitope recognized has been localized at the repeating unit domain ("RUD") of the cytoplasmic C-terminal part of the polypeptide.</p> <p>Reactivity on cultured cell lines: A-431, MDBK.</p>
Biological Information
- Clonality: Monoclonal
- Host: Mouse