In immunoblots of cytoskeletal preparations from human skin the antibody reacts specifically with a 160 kD polypeptide typical for Desmoglein 1. In immunolocalization studies the mab shows typical staining of suprabasal layers of the epidermis and special regions of fetal anagen hair follicles. The staining pattern observed corresponds to those obtained with pemphigus foliaceus patient sera. Cross-reaction with Desmogleins 2 and 3 was not detected
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: recombinant human Desmoglein 1 (extracellular part EII, EIII and EIV)
- Clone: Dsg1-P124
- Conjugate: unconjugated
- Isotype: IgG2a
- Quantity: 5 mL
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
- Immunohistochemistry (IHC)
- Western Blotting (WB)
