Product & ReviewsAntibodies
anti-Desmoglein 1 mouse monoclonal, Dsg1-P23, supernatant concentrate
Product Details
- Cat. No.
- 652110
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
In immunoblots of cytoskeletal preparations from human skin the antibody reacts specifically with a 160 kD polypeptide typical for Desmoglein 1. In immunolocalization studies the mab shows typical staining of suprabasal layers of the epidermis and special regions of fetal and anagen hair follicles. The staining pattern observed corresponds to those obtained with pemphigus foliaceus patient sera. Cross-reaction with Desmogleins 2 and 3 was not detected
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: recombinant human polypeptide Desmoglein 1 (extra-cellular part EII, EIII and EIV)
- Clone: Dsg1-P23
- Conjugate: unconjugated
- Isotype: IgG1
Handling
- Quantity: 500 µL
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Applications
- Immunohistochemistry (IHC)