Product & ReviewsAntibodies
anti-Desmoglein 3 mouse monoclonal, Dsg-G194, supernatant
Product Details
- Cat. No.
- 651112
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
In immunoblots of cytoskeletal preparations from human epidermis the antibody reacts specifically with a 140 kD polypeptide typical for Desmoglein 3. In immunolocalization studies the mab shows typical staining of basal and lower suprabasal layers of the epidermis and special regions of fetal and anagen hair follicles. The staining pattern observed corresponds to those obtained with pemphigus vulgaris patient sera. Cross-reaction with Desmogleins 1 and 2 was not detected
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: recombinant human polypeptide Desmoglein 3 (C-terminal aa 920-940 VSIPDPLQHGNYLVTETYSAS)
- Clone: Dsg-G194
- Conjugate: unconjugated
- Isotype: IgG1
Handling
- Quantity: 5 mL
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Applications
- Immunohistochemistry (IHC)
- Western Blotting (WB)