Anti-Erythropoietin monoclonal antibody, clone AE7A5
Product Details
- Cat. No.
- CABT-49123MH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mouse Anti-Human Erythropoietin monoclonal antibody for WB. Mouse anti Human Erythropoietin antibody, clone AE7A5 recognizes human erythropoietin (EPO) and binds to an epitope within the first 26 amino acids of the N-terminus of human urinary and human recombinant EPO. EPO is a 166 amino acid ~30 kDa glycoprotein hormone secreted primarily by the kidney that stimulates bone marrow erythropoiesis in response to hypoxia or anemia. The cDNAs for Epo have been cloned from many species and the mature proteins from the various species are highly conserved, exhibiting greater than 80% sequence identity at the amino acid level. Mouse anti Human Erythropoietin antibody, clone AE7A5 is the primary antibody sanctioned by the World Anti Doping Agency for the identification and evaluation of natural and recombinant erythropoietin by western blotting in biological samples. In addition to recognizing both recombinant and native human erythropoietin, clone AE7A5 cross reacts with zinc-alpha-2-glycoprotein, this reactivity is well separated from that of erythropoietin and does not interfere with the EPO testing assay. Applications：WB
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human, Rat
- Conjugate: Unconjugated
- Isotype: IgG2a
- Gene: 2056
Handling
- Quantity: 250 μg
- Storage: in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)