Anti-FLT1 monoclonal antibody, clone Flt-19
Product Details
- Cat. No.
- CABT-47861MH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mouse anti-Human FLT1 monoclonal antibody for IHC-Fr; ELISA; IP. This product specifically recognises an epitope within amino acid residues 1-251 located in the extracellular domain of human VEGF (vascular endothelial growth factor) receptor 1 (VEGFR-1), otherwise known as Flt-1, a tyrosine-kinase receptor expressed by almost all vascular endothelial cells and by some peripheral blood monocytes. VEGFR-1 acts as a receptor for members of the VEGF protein family, playing a key role in vascular development and the regulation of vascular permeability. The signal transduction cascade resulting from VEGFR-1 binding appears to differ from that of VEGFR-2 (KDR), since the proliferation of cells lacking VEGFR-1 can be induced by VEGFR-2 binding, whilst the proliferation of cells lacking VEGFR-2, cannot be induced by VEGFR-1 binding alone. Applications：IHC-Fr; ELISA; IP
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Conjugate: Unconjugated
- Isotype: IgG1
- Gene: 2321
Handling
- Quantity: 100 μg
- Storage: in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Western Blotting (WB)