Anti-Gαo Protein - Purified

Heterotrimeric G proteins, composed of Gα and Gβγ subunits, transmit signals from cell surface receptors to cellular effector enzymes and ion channels. The Gαo protein is the most abundant Gα subtype in the nervous system, but it is also found in the heart. Its function is not completely known, although it is required for regulation of N-type Ca2+ channels in GH3 cells and also interacts with GAP43, a major protein in growth cones, suggesting a role in neuronal pathfinding.

• Clonality: Monoclonal
• Host: Mouse
• Antigen: Antibody 2A reacts with bovine Gαo protein. Antibody showed 70% reactivity in human, 61% in rat and 54% in mouse of the bovine reactivity.
• Clone: 2A
• Conjugate: Purified
• Isotype: IgG1

• Quantity: 0.25 mg
• Storage: This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

• Immunohistochemistry (IHC)
• Western Blotting (WB)