Anti-GAPDH monoclonal antibody, clone 6C5 [Dylight® 800]
Product Details
- Cat. No.
- CABT-52173MR
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mouse Anti-Rabbit GAPDH monoclonal antibody for WB. Mouse anti Rabbit GAPDH antibody, clone 6C5 recognizes glyceraldehyde-3-phosphate dehydrogenase (GAPDH), a 36kD multifunctional protein whose main function is to catalyse the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin. Western Blotting is suitable for use as a loading control. Applications：WB
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: African Green Monkey, Cat (Feline), Chicken, Dog (Canine), Fish, Human, Mouse, Pig (Swine), Rabbit (Lapine), Rat, Sheep (Ovine), Tube-Nosed Bat, Vertebrate, Xenopus
- Conjugate: Dylight® 800
- Isotype: IgG1
- Gene: 100009074
Handling
- Quantity: 100 μg
- Storage: in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)