Anti-Human BA-R (CT)
Product Details
- Cat. No.
- B514
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BA, BLyS, TALL-1, THANK, and zTNF4.1-4 BA/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion.1,2 Two receptors, TACI and BCMA, for BA were originally identified. A third receptor was identified recently and designated BA-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BA and April, BA-R/BR3 is specific for BA and plays a predominant role in BA induced B cell development and survival. BA and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kB and c-jun N-terminal kinase.4
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Conjugate: Purified No Carrier Protein
Handling
- Quantity: 0.1 mg
- Storage: This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Applications
- ELISA (ELISA)
- Western Blotting (WB)