Anti-Human BMP-9

Bone morphogenetic protein (BMP-9) is also known as growth differentiation factor 2 (GDF2) is a protein that in humans encoded by the GDF2 gene. GDF2 belongs to the transforming growth factor beta (TGF-β) superfamily. BMP9 has a role in inducing and maintaining the ability of embryonal and adult tissues. Unlike with other BMP family proteins, the propeptide does not interfere with the biological activity of BMP9 and remains associated with the mature peptide after proteolytic cleavage. Another suggested role of BMP-9 could be a potent inducer of hepcidin in liver cells and could regulate iron metabolism. Mature human and mouse BMP-9 share 96% amino acid sequence identity.

• Clonality: Monoclonal
• Host: Mouse
• Reactivity: Human
• Clone: 360107
• Conjugate: Purified No Carrier Protein
• Isotype: IgG2b
• Gene: 2658

• Quantity: 100 µg
• Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.

• Blocking (BA)
• In Situ Hybridization (ISH)
• Mass Cytometry (CyTOF)