Anti-Human Cardiotrophin-1

Human CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Biologically active human CT-1 is synthesized as a 201 amino acid polypeptide lacking a hydrophobic N-terminal secretion signal sequence. Human and mouse CT-1 share 80% aa sequence identity and exhibit cross-species activity.

• Clonality: Polyclonal
• Host: Goat
• Reactivity: Human
• Antigen: Human CT-1 is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lungs.
• Conjugate: Antigen Affinity Purified
• Gene: 1489

• Quantity: 100 µg
• Storage: The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

• In Situ Hybridization (ISH)
• Mass Cytometry (CyTOF)
• Western Blotting (WB)