Product & ReviewsAntibodies

Anti-Human Cardiotrophin-1 -Biotin

Product Details

Cat. No.
C395-50 µg
Clonality
Polyclonal
Host
Goat
Leinco Technologies

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Description

Human CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Biologically active human CT-1 is synthesized as a 201 amino acid polypeptide lacking a hydrophobic N-terminal secretion signal sequence. Human and mouse CT-1 share 80% aa sequence identity and exhibit cross-species activity.

Biological Information

  • Clonality: Polyclonal
  • Host: Goat
  • Reactivity: Human
  • Conjugate: Biotin
  • Gene: 1489

Handling

  • Quantity: 50 µg
  • Storage: The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • In Situ Hybridization (ISH)
  • Mass Cytometry (CyTOF)
  • Neutralization (Neut)
  • Western Blotting (WB)
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