Product & ReviewsAntibodies
Anti-Human Caspase-8 Active Subunit (p18)
Product Details
- Cat. No.
- C1142
- Clonality
- Monoclonal
- Host
- Mouse
The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our Antibody Directory.
Description
Caspase-8 is a member of the caspase family of cysteine proteases and plays a key role in mediating Fas (CD95) and tumor necrosis factor–1 (TNFR-1) induced apoptosis. Activation of caspase 8 by proteolytic cleavage leads to the release of the active p18 and p10 subunits. These processed subunits associate to form an active enzyme.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: C81.349
- Conjugate: Purified
- Isotype: IgG2b
Handling
- Quantity: 0.2 mg
- Storage: This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Applications
- Immunohistochemistry (IHC)
- Western Blotting (WB)