Anti-Human CCR2 - APC
Product Details
- Cat. No.
- C1540
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CCR2, short for chemokine (C-C motif) receptor 2, is a chemokine receptor. CCR2 has also recently been designated CD192 (cluster of differentiation 192). This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: 48607
- Conjugate: Allophycocyanin (APC)
- Isotype: IgG2b
- Gene: 729230
Handling
- Quantity: 100 tests, 25 tests
- Storage: This Allophycocyanin (APC) conjugate is stable for at least twelve months when stored at 2-8°C protected from light. Do not freeze.
Applications
- Immunohistochemistry (IHC)