Anti-Human CCR8 (EL)
Product Details
- Cat. No.
- C1119
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and mouse CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Conjugate: Purified No Carrier Protein
Handling
- Quantity: 0.1 mg
- Storage: This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
- Specificity: 5
Applications
- Western Blotting (WB)
Performs well with the human cell lines
Amazing Antibody Solution for the Experiment
This is an amazing antibody which can effectively work with human cell lines. I am very happy to use it and this antibody provides me great results. Quite efficient, innovative, and productive with unique properties to have and successful implementation with the experiments. Happy to work with this antibody.
Review Date: 12 Dec 2022 | Leinco Technologies