IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
- Clone: GIR-208
- Conjugate: DyLight® 594
- Isotype: IgG1
- Gene: 3459
- Quantity: 50 µg
- Storage: This DyLight® 594 conjugate is stable when stored at 2-8°C. Do not freeze.
- In Situ Hybridization (ISH)