Product & ReviewsAntibodies
Anti-Human CD119 (IFN-γ Rα Chain) - Purified
Product Details
- Cat. No.
- I-442- 25 µg
- Clonality
- Monoclonal
- Host
- Mouse
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Description
IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
- Clone: GIR-208
- Conjugate: Purified
- Isotype: IgG1
Handling
- Quantity: 25 µg
- Storage: This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Applications
- Western Blotting (WB)