IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
- Clone: GIR-208
- Conjugate: GOLD, Low Endotoxin Functional Formulation
- Isotype: IgG1
- Quantity: 100 mg
- Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
