Product & ReviewsAntibodies
Anti-Human CD119 (IFN-γ Rα Chain) - Purified <i>In vivo </i>PLATINUM™ Functional Grade
Product Details
- Cat. No.
- G737- 100 mg
- Clonality
- Monoclonal
- Host
- Mouse
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Description
IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
- Clone: GIR-208
- Conjugate: Low Endotoxin Functional Formulation, PLATINUM
- Isotype: IgG1
- Gene: 3459
Handling
- Quantity: 100 mg
- Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.