Product & ReviewsAntibodies

Anti-Human CD14 - Purified <i>In vivo </i>GOLD™ Functional Grade

Product Details

Cat. No.
C370-1.0 mg
Clonality
Monoclonal
Host
Mouse
Leinco Technologies

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Description

CD14 is a 53-55 kD GPI-anchored single chain glycoprotein that plays a role in the clearance of gram-negative pathogens by interacting with other proteins, including TLR-4 and MD-2, to mediate the innate immune response to bacterial lipopolysaccharide (LPS). As a high-affinity receptor for LPS, it is involved in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD14 is expressed on monocytes, macrophages, dendritic cells, and granulocytes.
  • Clone: UCHM-1
  • Conjugate: GOLD, Low Endotoxin Functional Formulation
  • Isotype: IgG2a
  • Gene: 929

Handling

  • Quantity: 1.0 mg
  • Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Applications

  • In Situ Hybridization (ISH)
  • Western Blotting (WB)
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