Product & ReviewsAntibodies
Anti-Human CD14 - Purified <i>In vivo </i>GOLD™ Functional Grade
Product Details
- Cat. No.
- C370- 5.0 mg
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD14 is a 53-55 kD GPI-anchored single chain glycoprotein that plays a role in the clearance of gram-negative pathogens by interacting with other proteins, including TLR-4 and MD-2, to mediate the innate immune response to bacterial lipopolysaccharide (LPS). As a high-affinity receptor for LPS, it is involved in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD14 is expressed on monocytes, macrophages, dendritic cells, and granulocytes.
- Clone: UCHM-1
- Conjugate: GOLD, Low Endotoxin Functional Formulation
- Isotype: IgG2a
- Gene: 929
Handling
- Quantity: 5.0 mg
- Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Applications
- In Situ Hybridization (ISH)