Product & ReviewsAntibodies

Anti-Human CD2 - Purified <i>In vivo </i>GOLD™ Functional Grade

Product Details

Cat. No.
C365- 25 mg
Clonality
Monoclonal
Host
Mouse
Leinco Technologies

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Description

CD2 is a 45-59 kD type I transmembrane glycoprotein belonging to the Ig superfamily. CD2 is the receptor for LFA-3/CD58. CD2 serves as an adhesion receptor that binds to CD58; generating the activation of CD2-positive T cells and NK cells and in the regulation of their cytolytic activities. CD2 is a specific marker for T cells and NK cells. Hence, it can be used in immunohistochemistry to identify the occurrence of these cells in tissue sections. The vast majority of T cell lymphomas and leukemias express CD2 which makes it possible to distinguish these conditions from B-cell lymphomas.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD2 is present on normal peripheral blood lymphocytes, thymocytes, mature circulating T-cells and a subset of NK cells.
  • Clone: G11
  • Conjugate: GOLD, Low Endotoxin Functional Formulation
  • Isotype: IgG2a
  • Gene: 914

Handling

  • Quantity: 25 mg
  • Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Applications

  • Immunohistochemistry (IHC)
  • In Situ Hybridization (ISH)
  • Western Blotting (WB)
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