Product & ReviewsAntibodies
Anti-Human CD2 - Purified <i>In vivo </i>GOLD™ Functional Grade
Product Details
- Cat. No.
- C365- 25 mg
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD2 is a 45-59 kD type I transmembrane glycoprotein belonging to the Ig superfamily. CD2 is the receptor for LFA-3/CD58. CD2 serves as an adhesion receptor that binds to CD58; generating the activation of CD2-positive T cells and NK cells and in the regulation of their cytolytic activities. CD2 is a specific marker for T cells and NK cells. Hence, it can be used in immunohistochemistry to identify the occurrence of these cells in tissue sections. The vast majority of T cell lymphomas and leukemias express CD2 which makes it possible to distinguish these conditions from B-cell lymphomas.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD2 is present on normal peripheral blood lymphocytes, thymocytes, mature circulating T-cells and a subset of NK cells.
- Clone: G11
- Conjugate: GOLD, Low Endotoxin Functional Formulation
- Isotype: IgG2a
- Gene: 914
Handling
- Quantity: 25 mg
- Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Applications
- Immunohistochemistry (IHC)
- In Situ Hybridization (ISH)
- Western Blotting (WB)