Product & ReviewsAntibodies
Anti-Human CD22 - Biotin
Product Details
- Cat. No.
- C180- 200 µg
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Cluster of differentiation 22 also known as CD22 is a B-cell-restricted transmembrane protein, which acts as a negative regulator of B-cell signalling. CD22 also has lectin-like adhesive properties.1 CD22 is a good target to shorten the time required for Ab production, thereby augmenting host defense against acute infectious diseases as "universal vaccination."2
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: The CD22 antigen is expressed on >90% of peripheral blood B-cells.1 This antigen is not present on T-cells, monocytes or macrophages. CD22 is expressed on most peripheral B-cell lymphomas and leukemias including hairy cell leukemia, but not on the immature bone marrow type of leukemia.
- Clone: RFB-4
- Conjugate: Biotin
- Isotype: IgG1
- Gene: 933
Handling
- Quantity: 200 µg
- Storage: This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Applications
- In Situ Hybridization (ISH)