Cluster of differentiation 22 also known as CD22 is a B-cell-restricted transmembrane protein, which acts as a negative regulator of B-cell signalling. CD22 also has lectin-like adhesive properties.1 CD22 is a good target to shorten the time required for Ab production, thereby augmenting host defense against acute infectious diseases as "universal vaccination."2
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: The CD22 antigen is expressed on >90% of peripheral blood B-cells.1 This antigen is not present on T-cells, monocytes or macrophages. CD22 is expressed on most peripheral B-cell lymphomas and leukemias including hairy cell leukemia, but not on the immature bone marrow type of leukemia.
- Clone: RFB-4
- Conjugate: DyLight® 488
- Isotype: IgG1
- Gene: 933
- Quantity: 50 µg
- Storage: This DyLight® 488 conjugate is stable when stored at 2-8°C. Do not freeze.
- In Situ Hybridization (ISH)
