Product & ReviewsAntibodies
Anti-Human CD28
Product Details
- Cat. No.
- C1400-100 µg
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells.
- Clone: 37407
- Conjugate: Purified No Carrier Protein
- Isotype: IgG1
Handling
- Quantity: 100 µg
- Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Applications
- Immunohistochemistry (IHC)
- Neutralization (Neut)
- Western Blotting (WB)