Product & ReviewsAntibodies
Anti-Human CD28-Biotin
Product Details
- Cat. No.
- C1491
- Clonality
- Polyclonal
- Host
- Goat
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Description
CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.
Biological Information
- Clonality: Polyclonal
- Host: Goat
- Reactivity: Human
- Antigen: CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells.
- Conjugate: Biotin
- Gene: 940
Handling
- Quantity: 50 µg
- Storage: The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted bioin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Applications
- ELISA (ELISA)
- Western Blotting (WB)