Product & ReviewsAntibodies
Anti-Human CD28 - Purified <i>In vivo </i>GOLD™ Functional Grade
Product Details
- Cat. No.
- C2820
- Clonality
- Monoclonal
- Host
- Mouse
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Description
CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells.
- Clone: CD28.2
- Conjugate: Low Endotoxin Functional Formulation
- Isotype: IgG1 κ
- Gene: 940
Handling
- Quantity: 1.0 mg, 100 mg, 25 mg, 5.0 mg, 50 mg
- Storage: This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications
- Blocking (BA)
- ELISA (ELISA)
- Immunoprecipitation (IP)
- In Situ Hybridization (ISH)
- Western Blotting (WB)