Product & ReviewsAntibodies

Anti-Human CD28 - Purified <i>In vivo </i>GOLD™ Functional Grade

Product Details

Cat. No.
C2820- 50 mg
Clonality
Monoclonal
Host
Mouse
Leinco Technologies

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Description

CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells.
  • Clone: CD28.2
  • Conjugate: Low Endotoxin Functional Formulation
  • Isotype: IgG1 κ
  • Gene: 940

Handling

  • Quantity: 50 mg
  • Storage: This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications

  • Blocking (BA)
  • ELISA (ELISA)
  • Immunoprecipitation (IP)
  • In Situ Hybridization (ISH)
  • Western Blotting (WB)
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