Product & ReviewsAntibodies

Anti-Human CD3 (Clone UCHT-1) - Purified <i>In vivo </i>GOLD™ Functional Grade

Product Details

Cat. No.
C364
Clonality
Monoclonal
Host
Mouse
Leinco Technologies

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Description

CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Antigen: CD3 is expressed on human peripheral blood lymphocytes, splenic lymphocytes, and the majority of T-CLL and T-ALL cells.
  • Clone: UCHT-1
  • Conjugate: GOLD, Low Endotoxin Functional Formulation
  • Isotype: IgG1 κ
  • Gene: 916

Handling

  • Quantity: 1.0 mg, 100 mg, 25 mg, 5.0 mg, 50 mg
  • Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Applications

  • Activation (Act)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
  • In Situ Hybridization (ISH)
  • Mass Cytometry (CyTOF)
  • Western Blotting (WB)
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