Anti-Human CTGF-Biotin
Product Details
- Cat. No.
- C2438
- Clonality
- Polyclonal
- Host
- Goat
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Description
CTGF (connective tissue growth factor) is a cysteine-rich, matrix-associated, heparin-binding protein and a member of the CCN family of secreted cysteine rich regulatory proteins and is the major mitogenic and chemoattractant protein produced by umbilical vein and vascular endothelial cells. CTGF stimulates the proliferation and differentiation of chondrocytes, induces angiogenesis, promotes cell adhesion of fibroblasts, endothelial, and epithelial cells, and binds to IGF, TGF beta1, and BMP-4. Cell migration and adhesion are signaled through binding to specific cell surface integrins and to heparin sulfate proteoglycans CTGF, a lower molecular weight isoform containing the C-terminal portion of the full length CTGF protein, exerts full heparin binding, cell adhesion, and mitogenic CTGF activity.
Biological Information
- Clonality: Polyclonal
- Host: Goat
- Reactivity: Human
- Conjugate: Biotin
Handling
- Quantity: 50 µg
- Storage: The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve (12) months from date of receipt. The reconstituted biotin conjugate can be stored for at least four (4) weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Applications
- In Situ Hybridization (ISH)