Product & ReviewsAntibodies
Anti-Human Epo R - FITC
Product Details
- Cat. No.
- E302
- Clonality
- Monoclonal
- Host
- Mouse
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Description
The erythropoietin receptor is a transmembrane protein belonging to the member of the cytokine receptor family. The receptor is tyrosine phosphorylated upon binding by erythropoietin and associates with and activates the tyrosine kinase, JAK2, which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. EPO-R transmits signals important for both proliferation and differentiation along the erythroid lineage.1 Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: 38409
- Conjugate: Fluorescein (FITC)
- Isotype: IgG2b
- Gene: 2056
Handling
- Quantity: 100 tests
- Storage: This Fluorescein (FITC) conjugate is stable for at least twelve months when stored at 2-8°C protected from light. Do not freeze.
Applications
- ELISA (ELISA)
- Western Blotting (WB)