Anti-Human F1A-α (CT)
Product Details
- Cat. No.
- F143- 1 mg
- Clonality
- Polyclonal
- Host
- Rabbit
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Description
Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aα and FEM1b.1,2 F1Aα/FEM1β is the homologue of C. elegans sex determining protein FEM-1.1,2 FEM-1/F1Aα is cleaved by CED-3 and caspase.3 FEM-1/F1Aα associates with CED-4 and its mammalian homologue Apaf-1.3 Overexpression of F1Aα induces apoptosis. F1Aα is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aα is expressed in a variety of human and mouse tissues.1,2
Biological Information
- Clonality: Polyclonal
- Host: Rabbit
- Reactivity: Human
- Conjugate: Purified No Carrier Protein
Handling
- Quantity: 1 mg
- Storage: This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Applications
- Western Blotting (WB)