Product & ReviewsAntibodies
Anti-Human GDF-15
Product Details
- Cat. No.
- G667
- Clonality
- Polyclonal
- Host
- Goat
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Description
Growth differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes.1 GDF15 is also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB.2 GDF15 is predominantly expressed in the liver, with lower levels seen in some other tissues. Its expression in the liver is significantly up-regulated during injury of organs such as liver, kidney, heart and lung.1,2,3 GDF-15 is a promising new biomarker in idiopathic pulmonary arterial hypertension.4
Biological Information
- Clonality: Polyclonal
- Host: Goat
- Reactivity: Human
- Conjugate: Antigen Affinity Purified
- Gene: 9518
Handling
- Quantity: 100 µg, 25 µg
- Storage: The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Applications
- Western Blotting (WB)