Product & ReviewsAntibodies

Anti-Human ICOS

Product Details

Cat. No.
I-611
Clonality
Polyclonal
Host
Goat
Leinco Technologies

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Description

Inducible co-stimulator (ICOS) is an inducible homodimeric costimulator protein that is structurally and functionally related to CD28. It is a third member of the CD28/CTLA4 family and it is expressed on activated T cells.1ICOS regulates CD28-dependent and CD28-independent CD4 (+) subset (Th1 and Th2) responses.2 ICOS is a major regulator of the adaptive immune system and therefore, has a protective role in inflammatory autoimmune diseases.3

Biological Information

  • Clonality: Polyclonal
  • Host: Goat
  • Reactivity: Human
  • Conjugate: Antigen Affinity Purified
  • Gene: 29851

Handling

  • Quantity: 100 µg, 25 µg
  • Storage: The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

Applications

  • Neutralization (Neut)
  • Western Blotting (WB)
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