Product & ReviewsAntibodies

Anti-Human IL-16 - Biotin

Product Details

Cat. No.
I-271
Clonality
Polyclonal
Host
Goat
Leinco Technologies

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Description

IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and mouse IL-16 show significant cross-species reactivity.

Biological Information

  • Clonality: Polyclonal
  • Host: Goat
  • Reactivity: Human
  • Conjugate: Biotin
  • Gene: 3603

Handling

  • Quantity: 50 µg
  • Storage: The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

Applications

  • ELISA (ELISA)
  • Western Blotting (WB)
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