Product & ReviewsAntibodies
Anti-Human IL-18 BPa
Product Details
- Cat. No.
- I-622- 500 µg
- Clonality
- Monoclonal
- Host
- Mouse
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Description
IL-18-binding protein (IL-18BP) is a secreted glycoprotein that functions as a natural anti-inflammatory and immunosuppressive molecule neutralizing the effects of high IL18 levels during inflammation.1 There are four variants of IL-18BP and IL18BPa is the predominant form showing the highest affinity towards IL18.1, 2 IL-18 BPa has the potential to amplify anti-inflammatory actions of immunosuppressive drugs, and thus may prove to be a valuable novel pharmacological component in the treatment of human autoimmune diseases.3
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: 136033
- Conjugate: Purified No Carrier Protein
- Isotype: IgG1
Handling
- Quantity: 500 µg
- Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Applications
- ELISA (ELISA)
- Immunohistochemistry (IHC)
- In Situ Hybridization (ISH)
- Mass Cytometry (CyTOF)
- Neutralization (Neut)