Product & ReviewsAntibodies

Anti-Human IL-3 Rα

Product Details

Cat. No.
I-651- 500 µg
Clonality
Monoclonal
Host
Mouse
Leinco Technologies

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Description

Interleukin 3 receptor alpha (IL3RA), also known as CD123 (Cluster of Differentiation 123), is a type I transmembrane protein that is expressed on the large majority of progenitor cells. IL-3R alpha function can be defined by the activity of its ligand interleukin-3. IL-3 is a multipotent cytokine that promotes the development of hemopoietic progenitors into cells of the erythroid, myeloid and lymphoid lineages.1 CD123 may be a promising strategy for the preferential ablation of acute myelogenous leukemia (AML) cells.2

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Clone: 32703
  • Conjugate: Purified No Carrier Protein
  • Isotype: IgG1

Handling

  • Quantity: 500 µg
  • Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.

Applications

  • Depletion (Dep)
  • Immunoprecipitation (IP)
  • In Situ Hybridization (ISH)
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