Product & ReviewsAntibodies
Anti-Human IL-4 R alpha
Product Details
- Cat. No.
- I-638- 25 µg
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Interleukin 4 receptor (IL-4R) is a type I cytokine receptor that is expressed by lymphocytes and is well known for its role in immunomodulatory signaling and has also been documented on oligodendrocytes, suggesting involvement in glial cell interactions. IL-4R exerts a negative regulatory role on oligodendrocytes that when deleted results in enhanced myelin repair.1 IL-4R in brain tumors may serve as an attractive target for anticancer therapy.2
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: 25463
- Conjugate: Purified No Carrier Protein
- Isotype: IgG2a
Handling
- Quantity: 25 µg
- Storage: The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Applications
- Neutralization (Neut)
- Western Blotting (WB)