Anti-Human Lymphotoxin βR - Biotin
Product Details
- Cat. No.
- L232
- Clonality
- Polyclonal
- Host
- Goat
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Description
Lymphotoxin beta receptor (LTBR), a receptor for lymphotoxin, is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages. LTBR specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis. LTBR pathway is important in the development and maintenance of lymphoid structures. Blocking this pathway has proved beneficial in autoimmune diseases such as diabetes and rheumatoid arthritis.1
Biological Information
- Clonality: Polyclonal
- Host: Goat
- Reactivity: Human
- Conjugate: Biotin
- Gene: 4055
Handling
- Quantity: 50 µg
- Storage: The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Applications
- Western Blotting (WB)